Reducing the number of relapses of urolithiasis (hereinafter ICD) through the personalization of metaphylaxis based on the accurate determination of the composition of kidney stones

08 december 2021, 19:28
Secret know-how
Model, prototype
The Novosibirsk company has developed a unique method for analyzing the chemical composition of kidney stones.
The company offers contract manufacturing of test systems, the development of reagents according to the customer's specifications, assistance in the registration of medical devices.
The company is looking for a partner who is ready to conduct quality control on the QRT-SARS-CoV2v6 reagent kit for the isolation and detection of SARS-CoV-2 virus RNA in clinical material by real-time RT-PCR.

A particular problem of urolithiasis (Urolithiasis) is the high frequency of recurrent stone formation. According to statistics, after 1 year, about 10% of patients have a relapse, after five years - 50% of patients. Removal of stones does not guarantee the absence of possible recurrent stone formation.

Patients at high risk of stone formation need to carry out specific prevention of relapse, which, as a rule, is medication and is based on an analysis of the composition of the stone. (Clinical guidelines EAU / 2017 (European Association of Urology))

Today, the analysis of the composition of stones is not mandatory by medical standards, and therefore little known to doctors and patients. The high cost of equipment, the complexity of the analysis, the lack of a knowledge base and research are the result of low qualifications of specialists in this area.

The project for the study of the mineralization of the human body (urolithiasis, ICD) - represents the most modern methods of analyzing the chemical composition of kidney stones, using IR spectrometry and X-ray phase analysis. The result of this analysis is a protocol indicating the name of the mineral and its percentage in the biomaterial (stone).

Based on the results of a qualitatively conducted analysis, the urologist determines the type of stone and is able to accurately prescribe further preventive and anti-relapse treatment of patients with ICD, thereby minimizing the risk of re-formation of stone in the human body.

Innovative aspects

Our laboratory has the following advantages:

1) Extensive experience: more than 20,000 studies have been carried out

2) The accuracy of the XRF method is 70% higher than other methods

3) For more than 170 samples, a relationship was established between the composition of the urolith and data from the medical history

4) Highly qualified staff guarantees the accuracy of research

Measurement methods | | Reference materials , Biological sciences , Measurements and standards
Measurements and standards